Is Stinging Nettle Root a DHT Blocker?

WrittenbyLuat Duong
Last updated

Stinging nettle, scientifically known as Urtica dioica, is a versatile plant that has been used for centuries in traditional medicine and natural remedies. One of the potential benefits of stinging nettle root that has gained attention in recent years is its potential as a natural DHT blocker.

Is Stinging Nettle Root a DHT Blocker?

Yes, stinging nettle root is considered a natural DHT blocker, which means it has the ability to inhibit the production or activity of dihydrotestosterone (DHT), a hormone that plays a significant role in hair loss and other conditions.

What is DHT and Its Role in Hair Loss?

DHT is a potent androgen (male sex hormone) derived from testosterone. It is formed through an enzymatic process involving the enzyme 5α-reductase. While DHT is necessary for normal male development and functions, an excess or heightened sensitivity to DHT can lead to various issues, including pattern hair loss (androgenetic alopecia).

In individuals with a genetic predisposition to male or female pattern baldness, DHT can bind to receptors in hair follicles, causing them to shrink and eventually stop producing new hair. This process leads to progressive thinning and baldness in susceptible areas, such as the scalp or facial regions.

Mechanisms of Action of Stinging Nettle Root as a DHT Blocker

Stinging nettle root contains several compounds that contribute to its potential as a DHT blocker, including:

  • Lignans: These plant compounds found in nettle root have been shown to inhibit the activity of the 5α-reductase enzyme, which is responsible for converting testosterone into DHT.
  • Beta-sitosterol: A plant sterol present in nettle root that may help block the binding of DHT to receptors in hair follicles, preventing its harmful effects.
  • Antioxidants: Nettle root is rich in antioxidants, such as polyphenols and flavonoids, which can help protect hair follicles from oxidative stress and inflammation caused by excess DHT.

By inhibiting the production of DHT and reducing its activity, stinging nettle root may potentially slow down or prevent further hair loss in individuals affected by androgenetic alopecia.

Research and Studies on Stinging Nettle Root as a DHT Blocker

Several studies have explored the potential of stinging nettle root as a natural DHT blocker, with promising results:

  • A study published in the journal "Phytomedicine" found that an extract of stinging nettle root effectively inhibited 5α-reductase activity, suggesting its potential as a DHT blocker.
  • Another study in the "Journal of Cosmetic Dermatology" evaluated the effects of a topical formulation containing stinging nettle root extract on men with androgenetic alopecia. The results showed significant improvements in hair growth and reduced hair shedding.
  • A review published in the "International Journal of Molecular Sciences" highlighted the potential of stinging nettle root extract as a natural alternative to conventional DHT-blocking medications used for treating hair loss.
Why you can trust Scandinavian Biolabs?
TrichoAI Hair Loss Analysis
Our free, anonymous and dermatologist-developed AI analyzes your hair loss in 30 seconds, suggesting personalized solutions to combat thinning. Understanding your hair condition has never been easier.
Yes, I want to fix hair loss

Using Stinging Nettle Root for Hair Loss

While stinging nettle root shows promise as a natural DHT blocker, it's important to note that its effectiveness may vary from individual to individual, and more research is needed to fully understand its mechanisms and optimal dosages.


Stinging nettle root supplements are widely available in various forms, such as capsules, tablets, or tinctures. It's recommended to follow the dosage instructions provided on the product label or consult with a healthcare professional for guidance on appropriate dosages.

Topical Applications

Some hair care products, such as shampoos, conditioners, or serums, may contain stinging nettle root extract as an ingredient. Applying these products directly to the scalp may help deliver the potential DHT-blocking compounds more effectively to the hair follicles.

Combination Therapy

Stinging nettle root supplements or topical products may be used in combination with other natural or conventional hair loss treatments for enhanced effectiveness. However, it's important to consult with a healthcare professional before combining different treatments to avoid potential interactions or adverse effects.

Precautions and Safety Considerations

While stinging nettle root is generally considered safe for most individuals when consumed in appropriate amounts, it's important to exercise caution and consult with a healthcare professional, especially if you have any underlying medical conditions or are taking medications. Potential side effects of stinging nettle root may include digestive issues, fluid retention, and allergic reactions in some individuals.

By understanding the potential benefits and mechanisms of stinging nettle root as a natural DHT blocker, individuals affected by hair loss can explore this herbal remedy as a complementary or alternative approach to managing their condition. However, it's essential to consult with a healthcare professional for personalized guidance and to ensure safe and appropriate use.

Tired of Thinning Hair? Try a Clinically Tested Serum.

Looking for a natural way to regrow hair and achieve a thicker, fuller head of hair? Ditch the stinging nettle for hair loss – Bio-Pilixin Serum is a drug-free hair activation serum that delivers clinically tested results.

Here's why Bio-Pilixin is superior:

  • Clinically Tested Results: 93% of users saw a reduction in hair loss, and 73% experienced increased hair density.
  • Safe and Natural: Unlike harsh chemicals, Bio-Pilixin uses plant growth factors derived from stem cell technology to nourish hair follicles and stimulate growth.
  • Fast-Acting: See visible results in as little as 45 days (most typically see results within 150 days).

Stop wasting time on unproven remedies. Bio-Pilixin is the safe, natural serum you've been searching for.

Bio-Pilixin® Activation Serum | For Men
Bio-Pilixin® Activation Serum | For Men
Drug-free & clinically tested
Bio-Pilixin® Activation Serum | For Women
Bio-Pilixin® Activation Serum | For Women
Drug-free & clinically tested

Read more:

Luat Duong

Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.