What Are the Side Effects of Pumpkin Seed Oil?

WrittenbyLuat Duong
Last updated

Pumpkin seed oil has gained popularity as a natural supplement due to its potential health benefits, including promoting hair growth, supporting prostate health, and reducing inflammation. While generally considered safe, it's essential to be aware of the potential side effects of pumpkin seed oil, as with any supplement or natural remedy.

What are the side effects of pumpkin seed oil?

The most common side effects of pumpkin seed oil include digestive issues such as nausea, diarrhea, and stomach cramps, especially when consumed in large amounts. Other potential side effects may include headaches, allergic reactions, and interactions with certain medications. However, when consumed in moderation, pumpkin seed oil is generally well-tolerated.

Digestive Discomfort

One of the most commonly reported side effects of pumpkin seed oil is digestive discomfort. This can manifest in various ways, including:

  • Nausea: Some individuals may experience nausea or feelings of queasiness after consuming pumpkin seed oil, particularly if taken on an empty stomach or in large doses.
  • Diarrhea: Excessive intake of pumpkin seed oil can lead to diarrhea or loose stools, as the oil can have a laxative effect for some people.
  • Stomach Cramps: Consuming large amounts of pumpkin seed oil may cause stomach cramps or abdominal discomfort in certain individuals.

To minimize digestive issues, it's recommended to start with a low dose of pumpkin seed oil and gradually increase it as tolerated. Additionally, taking the oil with meals can help reduce the risk of digestive discomfort.

Allergic Reactions

While rare, some individuals may experience allergic reactions to pumpkin seed oil. Symptoms of an allergic reaction can include hives, rashes, itching, swelling, or difficulty breathing. If you experience any severe allergic reactions, it's crucial to seek medical attention immediately.


In some cases, consuming pumpkin seed oil may trigger headaches or migraines in individuals who are susceptible to these conditions. If you notice a pattern of headaches after taking pumpkin seed oil, it's advisable to discontinue use and consult with a healthcare professional.

Interactions with Medications

Pumpkin seed oil has the potential to interact with certain medications, which can either reduce their effectiveness or increase the risk of side effects. Some medications that may interact with pumpkin seed oil include:

  • Blood Thinners: Pumpkin seed oil may increase the risk of bleeding when taken with blood-thinning medications like warfarin or aspirin.
  • Cholesterol-lowering Drugs: There is a possibility that pumpkin seed oil may interact with cholesterol-lowering medications, such as statins, and affect their efficacy.
  • Diabetes Medications: Pumpkin seed oil may interfere with the action of certain diabetes medications, leading to fluctuations in blood sugar levels.

If you are taking any medications, it's essential to consult with a healthcare professional before incorporating pumpkin seed oil into your routine to avoid potential interactions and ensure your safety.

Precautions and Moderation

While pumpkin seed oil is generally considered safe when consumed in moderation, it's important to follow the recommended dosage guidelines and listen to your body's responses. If you experience any adverse side effects or have concerns, it's advisable to discontinue use and consult with a healthcare professional.

Additionally, individuals with certain medical conditions, such as kidney or liver disease, should exercise caution and consult with a healthcare professional before taking pumpkin seed oil supplements.

Why you can trust Scandinavian Biolabs?
TrichoAI Hair Loss Analysis
Our free, anonymous and dermatologist-developed AI analyzes your hair loss in 30 seconds, suggesting personalized solutions to combat thinning. Understanding your hair condition has never been easier.
Yes, I want to fix hair loss


Pumpkin seed oil can offer a range of potential health benefits, but it's essential to be aware of the possible side effects, including digestive discomfort, allergic reactions, headaches, and interactions with certain medications. By consuming pumpkin seed oil in moderation, starting with low doses, and consulting with a healthcare professional, you can minimize the risk of adverse effects and safely incorporate this natural supplement into your wellness routine.

Ditch the DIY: Upgrade your hair growth routine.

Rosemary oil has potential, but what if there was a clinically tested serum formulated by experts? Bio-Pilixin® Activation Serum goes beyond trends and folklore.

Our drug-free formula, packed with plant growth factors, it:

  • Helps reduce hair loss in 93% of users (clinically tested!)
  • Encourages new hair growth
  • Creates the ideal environment for your hair to grow

Skip the mess and uncertainty of DIY. Bio-Pilixin® is safe, effective, and backed by science. Give your hair the natural boost it deserves.

Bio-Pilixin® Activation Serum | For Men
Bio-Pilixin® Activation Serum | For Men
Drug-free & clinically tested
Bio-Pilixin® Activation Serum | For Women
Bio-Pilixin® Activation Serum | For Women
Drug-free & clinically tested

Read more:

Luat Duong

Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.