Which Vitamin Kills DHT?

WrittenbyLuat Duong
Last updated

Hair loss, particularly androgenetic alopecia (male and female pattern baldness), is a common concern that affects millions of individuals worldwide. While various factors contribute to this condition, one of the primary culprits is dihydrotestosterone (DHT), a hormone derived from testosterone. As the search for effective hair loss treatments continues, many people are exploring natural remedies, including vitamins. But can vitamins really help combat DHT and its effects on hair follicles? If so, which vitamin is the most potent in killing DHT? Let's delve into this topic and uncover the potential of vitamins in addressing this hair loss challenge.

Which Vitamin Kills DHT?

While no single vitamin has been definitively proven to "kill" or completely eliminate DHT, research suggests that vitamin B6 (pyridoxine) may play a role in reducing DHT levels and potentially mitigating its effects on hair loss.

Understanding DHT and Its Role in Hair Loss

Before exploring the role of vitamins in managing DHT levels, it's essential to understand the significance of this hormone in hair loss. DHT, or dihydrotestosterone, is a byproduct of the male hormone testosterone. While it plays a crucial role in male sexual development, DHT can also have adverse effects on hair follicles.

In individuals with a genetic predisposition to androgenetic alopecia, hair follicles become hypersensitive to DHT. This sensitivity causes the hair follicles to shrink, resulting in shorter hair growth cycles and eventually leading to thinning hair or baldness.

The Potential of Vitamin B6 in Reducing DHT

Among the various vitamins, vitamin B6 (pyridoxine) has garnered attention for its potential role in reducing DHT levels. Here's why vitamin B6 is considered a promising candidate:

Inhibition of 5-Alpha-Reductase

Vitamin B6 is believed to inhibit the activity of 5-alpha-reductase, the enzyme responsible for converting testosterone into DHT. By reducing the production of DHT, vitamin B6 may help prevent or slow down the progression of androgenetic alopecia.

Clinical Studies and Promising Results

Several studies have explored the link between vitamin B6 and DHT levels. A study published in the Journal of Steroid Biochemistry and Molecular Biology found that individuals with higher levels of vitamin B6 had lower levels of DHT in their blood.

Another study published in the journal Nutrients examined the effects of vitamin B6 supplementation on participants with androgenetic alopecia. The researchers found that those who received vitamin B6 supplements experienced a significant reduction in hair shedding and improved hair growth compared to the placebo group.

Other Vitamins and Their Potential Role in Hair Loss

While vitamin B6 shows promise in reducing DHT levels, other vitamins may also play a supporting role in promoting hair health and combating hair loss. Here are a few notable examples:

Vitamin C

Vitamin C is a powerful antioxidant that can help neutralize free radicals and reduce oxidative stress, which can contribute to hair loss. Additionally, vitamin C is involved in the production of collagen, a protein essential for healthy hair growth.

Biotin (Vitamin B7)

Biotin, also known as vitamin B7, is often touted as a hair growth supplement. While it doesn't directly affect DHT levels, biotin plays a crucial role in supporting healthy hair, skin, and nails by promoting keratin production.

Vitamin D

Vitamin D deficiency has been linked to various health issues, including hair loss. Maintaining adequate vitamin D levels may help support hair growth and prevent excessive shedding.

Incorporating Vitamins into Your Hair Care Regimen

If you're interested in using vitamins to potentially reduce DHT levels and combat hair loss, there are several ways to incorporate them into your routine:

Dietary Sources

Consuming a balanced diet rich in vitamin-dense foods can help ensure you're getting adequate levels of essential vitamins. For example, vitamin B6 can be found in foods like poultry, fish, whole grains, and legumes, while vitamin C is abundant in citrus fruits, berries, and leafy greens.


If dietary sources are not sufficient, you may consider taking vitamin supplements, particularly vitamin B6 and other hair-friendly vitamins like biotin and vitamin C. However, it's crucial to consult with a healthcare professional to determine the appropriate dosage and ensure there are no contraindications with any existing medical conditions or medications.

Topical Application

Some individuals may choose to apply vitamin-enriched hair products, such as serums or masks, directly to the scalp. These products can help nourish the hair follicles and potentially support hair growth.

Precautions and Considerations

While vitamins are generally considered safe when taken in appropriate amounts, it's important to keep a few precautions in mind:


Taking excessive amounts of certain vitamins, particularly fat-soluble vitamins like vitamin A and vitamin D, can lead to adverse effects. It's crucial to follow recommended dosages and consult with a healthcare professional before taking high-dose supplements.

Individual Variations

Everyone's body responds differently to vitamins and supplements. If you don't notice any improvements in hair growth or slowing down of hair loss after several months of consistent use, it may be beneficial to consult with a dermatologist or trichologist for alternative treatment options.

A Holistic Approach to Hair Loss

While vitamins can be a valuable addition to your hair care regimen, addressing hair loss often requires a multifaceted approach. Here are some additional measures to consider:

Balanced Diet and Supplements

In addition to vitamins, ensuring you're getting adequate nutrients, such as protein, iron, zinc, and other essential vitamins and minerals, can support overall hair health.

Stress Management

Chronic stress can contribute to hair loss, so incorporating stress management techniques like meditation, exercise, or counseling can be beneficial.

Gentle Hair Care Practices

Adopting gentle hair care practices, such as minimizing heat styling, avoiding tight hairstyles, and using a wide-tooth comb or a brush with soft bristles, can help prevent further breakage and promote healthy hair growth.

Seek Professional Guidance

If you're experiencing significant hair loss or thinning, it's essential to consult with a dermatologist or a trichologist (a specialist in hair and scalp disorders). They can help identify the underlying cause and provide appropriate treatment recommendations, which may include prescription medications or other targeted therapies.

In conclusion, while no single vitamin has been definitively proven to "kill" or completely eliminate DHT, research suggests that vitamin B6 may play a role in reducing DHT levels and potentially mitigating its effects on hair loss. However, it's important to approach vitamin supplementation as part of a comprehensive hair care regimen that addresses underlying causes and incorporates a balanced diet, stress management, and gentle hair care practices. Additionally, seeking professional guidance from a healthcare provider can ensure you're taking appropriate steps to address your specific hair loss concerns effectively and safely.

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Luat Duong

Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.