Is Pumpkin Seed Oil DHT Blocker?

WrittenbyLuat Duong
Last updated

Hair loss, particularly androgenetic alopecia (male and female pattern baldness), can be a frustrating and often distressing experience. While various factors contribute to this type of hair loss, one of the primary culprits is dihydrotestosterone (DHT), a hormone derived from testosterone. As the search for effective hair loss treatments continues, many individuals are turning to natural remedies, including pumpkin seed oil. But does this versatile oil have the ability to block DHT, the hormone at the root of androgenetic alopecia? Let's delve into the science and explore whether pumpkin seed oil can be considered a DHT blocker.

Is Pumpkin Seed Oil a DHT Blocker?

Yes, pumpkin seed oil is believed to have DHT-blocking properties, making it a potential natural remedy for combating androgenetic alopecia (male and female pattern baldness). However, more research is needed to fully understand its effectiveness and mechanism of action.

Understanding DHT and Its Role in Hair Loss

Before we explore pumpkin seed oil's potential as a DHT blocker, it's essential to understand the role of DHT in hair loss. DHT, or dihydrotestosterone, is a byproduct of the male hormone testosterone. While it plays an important role in male sexual development, DHT can also have adverse effects on hair follicles.

In individuals with a genetic predisposition to androgenetic alopecia, hair follicles become hypersensitive to DHT. This sensitivity causes the hair follicles to shrink, resulting in shorter hair growth cycles and eventually leading to thinning hair or baldness.

Pumpkin Seed Oil and DHT Inhibition

Several studies have suggested that pumpkin seed oil may have the ability to inhibit the activity of 5-alpha-reductase, the enzyme responsible for converting testosterone into DHT. By potentially reducing the production of DHT, pumpkin seed oil could help prevent or slow down the progression of androgenetic alopecia.

The compounds in pumpkin seed oil that are believed to contribute to its DHT-blocking properties include:


Pumpkin seed oil is rich in plant sterols, also known as phytosterols, such as beta-sitosterol. These compounds have been shown to have anti-androgenic properties, meaning they can potentially inhibit the activity of androgens like DHT.


Cucurbitins are a group of naturally occurring compounds found in pumpkin seeds and their oils. Some research suggests that cucurbitins may have the ability to inhibit 5-alpha-reductase, the enzyme responsible for converting testosterone into DHT.

Clinical Studies and Potential Benefits

While the research on pumpkin seed oil as a DHT blocker is still relatively limited, some studies have shown promising results:

Improved Hair Growth

A study published in the Journal of Cosmetic Dermatology found that men with androgenetic alopecia who supplemented with pumpkin seed oil experienced improvements in hair growth and increased hair counts compared to those who received a placebo.

Reduced Hair Loss

Another study published in the journal Evidence-Based Complementary and Alternative Medicine reported that pumpkin seed oil supplements helped reduce hair loss in men with androgenetic alopecia.

Incorporating Pumpkin Seed Oil into Your Hair Care Routine

If you're interested in using pumpkin seed oil as a potential DHT blocker to combat hair loss, there are several ways to incorporate it into your hair care routine:

Oral Supplementation

Pumpkin seed oil supplements are available in capsule or liquid form. Taking these supplements orally can help provide the beneficial compounds to the body and potentially support hair growth from within.

Topical Application

Applying pumpkin seed oil directly to the scalp can help nourish the hair follicles and potentially inhibit DHT activity. Many individuals massage a few drops of the oil into their scalp and leave it on for an hour or overnight before shampooing.

Hair Masks or Treatments

Pumpkin seed oil can also be incorporated into hair masks or deep conditioning treatments, helping to nourish and strengthen the hair strands while potentially promoting hair growth.

Precautions and Considerations

While pumpkin seed oil is generally considered safe for use, it's important to keep a few precautions in mind:

Patch Test

Before incorporating pumpkin seed oil into your hair care routine, it's recommended to perform a patch test on a small area of skin to check for any potential allergic reactions or sensitivities.

Quality and Purity

When purchasing pumpkin seed oil, it's essential to choose high-quality, pure, and cold-pressed products from reputable sources to ensure maximum efficacy and safety.

Individual Variations

While pumpkin seed oil shows promise as a DHT blocker, individual responses may vary. If you don't notice any improvements in hair growth or slowing down of hair loss after several months of consistent use, it may be beneficial to consult with a dermatologist or trichologist for alternative treatment options.

A Holistic Approach to Hair Loss

While pumpkin seed oil can be a valuable addition to your hair care regimen, addressing hair loss often requires a multifaceted approach. Here are some additional measures to consider:

Balanced Diet and Supplements

Ensuring you're getting adequate nutrients, such as protein, iron, zinc, and vitamins like biotin and vitamin D, can support healthy hair growth.

Stress Management

Chronic stress can contribute to hair loss, so incorporating stress management techniques like meditation, exercise, or counseling can be beneficial.

Gentle Hair Care Practices

Adopting gentle hair care practices, such as minimizing heat styling, avoiding tight hairstyles, and using a wide-tooth comb or a brush with soft bristles, can help prevent further breakage and promote healthy hair growth.

Seek Professional Guidance

If you're experiencing significant hair loss or thinning, it's essential to consult with a dermatologist or a trichologist (a specialist in hair and scalp disorders). They can help identify the underlying cause and provide appropriate treatment recommendations.

In conclusion, pumpkin seed oil is believed to have DHT-blocking properties, making it a potential natural remedy for combating androgenetic alopecia (male and female pattern baldness). While more research is needed to fully understand its effectiveness and mechanism of action, the compounds found in pumpkin seed oil, such as phytosterols and cucurbitins, have shown promising results in inhibiting the activity of 5-alpha-reductase, the enzyme responsible for converting testosterone into DHT. However, it's important to approach pumpkin seed oil as part of a comprehensive hair care regimen that addresses underlying causes and incorporates a balanced diet, stress management, and gentle hair care practices.

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Luat Duong

Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.