7 Best & Proven DHT Blocking Serums In 2024

Medically reviewed by Dr. Amy Revene M.B.B.S.
Written by Our Editorial Team
Last updated

In the ever-evolving realm of hair care solutions, the demand for effective treatments has spurred innovations like DHT-blocking serums.

These hair elixirs have emerged as a powerful weapon in the battle against hair loss and thinning using natural DHT blockers to combat the issue. 

Whether you're experiencing the first signs of a receding hairline or are in the throes of significant hair loss, DHT-blocking serums could be a helpful option for you.

Backed by science and trusted by experts, DHT blockers target the hormone called DHT short for dihydrotestosterone. These blockers are designed to combat hair loss at its root cause. 

We have scoured the market and curated a list of the top 7 DHT blocking serums of 2024.

These best and proven solutions provide an efficient defense against hair loss, infusing your scalp with nourishing elements for healthier, fuller hair.

Summary

In the quest to reclaim hair health, vitality, and density, DHT-blocking serums have emerged as a beacon of hope, particularly for those grappling with hair loss and thinning.

With scientifically-backed formulas and potent natural ingredients, these serums are an effective solution to significantly reduce hair loss, by neutralizing DHT - the primary culprit of hair damage.

The 2024 market is teeming with innovative, potent DHT-blocking serums, each promising a unique blend of benefits and proven effectiveness.

While PURA D'OR, MDhair, FOLIGAIN, Guyology labs, Re-Grow, and Propidren by Hairgenics are making waves in the hair care industry, the Bio-Pilixin Serum also stands out as a safer and plant-powered alternative for DHT blocking. 

Remember, consistency is key when using these products. It's also beneficial to incorporate ingredients like pumpkin seed oil that have been associated with hair health into your routine.

Also, don't forget to include beneficial lifestyle changes such as a balanced diet rich in nutrients and DHT-blocking elements like green tea for a holistic approach to hair health.

How does DHT-blocking serum work?

dht blocking serum

DHT-blocking serums work by inhibiting the production of dihydrotestosterone (DHT), a hormone that contributes to hair loss. They typically contain natural ingredients that interfere with the conversion of testosterone into DHT, reducing its levels in the scalp and thereby preventing hair follicles from shrinking.

DHT is an androgen hormone that has been linked to both female and male pattern baldness or androgenic alopecia.

It binds to receptors in hair follicles, causing them to shrink over time and eventually stop producing hair. This is where DHT blocking serums come into play. 

These topical solutions are formulated with specific ingredients, often natural extracts like saw palmetto or nettle leaf, that inhibit the enzyme 5-alpha reductase.

This enzyme which converts testosterone into DHT, so by blocking its action, the serums can effectively reduce the levels of DHT in the scalp.

By reducing DHT levels, DHT-blocking serums can slow or halt the miniaturization of hair follicles, promoting healthier and more resilient hair growth.

While these serums won't necessarily regrow hair that's already lost, they can help preserve existing hair and slow down the thinning process. 

It's important to note that these serums can take a few months to show visible effects as hair growth is a slow process.

But with consistent use, they can make a significant difference in hair thickness and health.

Top dht blocking serums in 2024

1. PURA D'OR Scalp Therapy Energizing Scalp Serum

dht blocker serum

Unleash the power of an exotic concoction of extracts and nutrients with the PURA D'OR Scalp Therapy Energizing Scalp Serum.

It's no ordinary serum - it’s a potent elixir that transforms your hair from the root to the tip, reducing thinning and enhancing thickness.

Key ingredients such as coffee extract, catalase, and cayenne invigorate the scalp and enrich the roots, resulting in healthier, stronger hair.

Moreover, the blend of amla, tea Tree, kahai seed, sacha inchi seed, and bilberry penetrates the scalp with ease, bringing forth lush, healthy strands.

The serum also boasts potent DHT blockers and an Apple Stem Cell formula that combats scalp acne and promotes stronger hair

This formula aims to support existing hair and may help in maintaining hair density. Witness your hair's transformation with every use.

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2. MDhair Restore Serum

dht blocking serum

The MDhair Restore Serum steps in as a powerful hair ally, packed with DHT blockers that stimulate and strengthen hair follicles. But that's not all.

The serum's unique formula features biomimetic copper peptides, saw palmetto extract, panax ginseng root, rosemary leaf oil, hydrolyzed rice, and oat proteins, biotin, and vitamin B5.

This potent blend does more than just hinder testosterone's conversion to DHT; it elevates scalp health and boosts hair density.

Natural ingredients in this serum aim to support your hair follicles, contributing to the appearance of thicker, healthier hair.

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3. FOLIGAIN DHT Blocker Serum with 12% Trichogen

best dht blocking serum

 FOLIGAIN's DHT Blocker Serum with 12% Trichogen stands tall as a champion in hair care. This potent serum caters to men and women grappling with thinning hair, offering a solution that doesn't just promise but delivers.

With a formulation that effectively blocks DHT, this serum halts hair loss and spurs vigorous natural hair growth.

The power-packed Trichogen nutrient complex, coupled with Acetyl Tyrosine, panax ginseng root extract, biotin, and soy protein, forms an unparalleled blend that reinforces hair follicles, enhances scalp health, and conditions hair for natural growth.

Acetyl Tyrosine acts as a hair growth stimulant, skin cell fortifier, and a vital player in DHT inhibition.

Free from harsh parabens, sulfates, and phthalates, this serum is gentle on your scalp while imparting powerful results.

With FOLIGAIN's DHT Blocker Serum, experience an ethically sound and effective hair care solution that rejuvenates your scalp and revitalizes your hair.

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4. Guyology labs Biotin Hair Growth Serum

hair serum

With a mission to revitalize hair growth, Guyology Labs presents their Biotin Hair Growth Serum.

This serum boasts clinically proven natural growth ingredients that invigorate hair growth for fuller, thicker, and stronger hair within just three months. 

The proprietary formula is a potent hair root stimulator growth serum that targets DHT - one of the primary hormones responsible for hair loss.

By blocking DHT, it reduces hair fall, loss, and shedding, stimulating new hair growth and reinforcing existing follicles.

This serum is power-packed with effective DHT blockers like saw palmetto extract, biotin, and vitamin E for thicker, stronger hair, and caffeine and rosemary for a stimulated healthy scalp.

It is quick and easy to apply with its non-greasy formula that swiftly penetrates the hair shaft and scalp. This creates strength from within to catalyze new growth, improve hair density, and promote regrowth. 

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5. Re-Grow Anti Hair loss & Rapid Growth Serum With Natural DHT Blocker

hair serum

The Re-Grow Anti Hair Loss Serum is a potent blend designed to combat hair loss.

Its unique formula blocks DHT, a primary cause of hair thinning, thereby stimulating dormant hair follicles on the scalp for rapid growth.

With its scientifically-proven DHT blockers, it effectively stops hair loss and promotes hair regrowth in both men and women, improving hair density.

Key ingredients like Saw Palmetto prevent DHT production, while biotin strengthens brittle hair and encourages the growth of healthy hair and skin cells.

The serum's unique blend of active ingredients creates a follicle-boosting effect that nurtures natural, healthy hair growth. It thickens fine hair, reduces hair loss, and balances an oily scalp by restoring nutrients to hair follicles.

Consistent usage over three months will yield the best results, all backed by a 100% money-back guarantee for a risk-free trial.

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6. Propidren by Hairgenics Hair Growth Serum

dht blocking serum

Provided by Hairgenics is a revolutionary hair growth serum specially formulated to address hair loss caused by DHT.

This serum works by directly delivering essential nutrients to nourish the scalp, hair, and hair follicles, naturally promoting follicular growth and hair thickening.

With just two daily applications of 1ml, it effectively blocks DHT's adverse effects, energizing the scalp to produce stronger, thicker hair.

The unique composition of Propidren includes natural ingredients known for their DHT-inhibiting properties, targeting DHT production at the hair follicles.

This serum is particularly beneficial as we age and experience increased DHT levels leading to hair thinning and loss.

It offers a dual-action solution when combined with Propidren supplements, providing an intensive, systemic, and topical treatment against hair loss.

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7. Ultrax Labs Hair Plush Serum

dht blocker

This innovative hair serum by Ultrax Labs stands out with its unique caffeine-infused formula.

It's an advanced hair treatment that supports a healthy hair growth cycle while minimizing DHT's effects on your hair follicles.

The Hair Plush serum is designed to stimulate the scalp and invigorate hair follicles directly, thanks to its unique blend of ingredients.

Its key ingredient, caffeine, extends the life cycle of hair follicles, encouraging healthier, thicker hair. In addition to blocking DHT, the formula is also enriched with Hydrolyzed Keratin, which can increase the thickness of your individual hair strands for a fuller look.

Notably, the serum is safe for everyday use and for all hair types. Its formula is hypoallergenic, non-irritating, and free of harsh chemicals, making it a great option for those with sensitive scalps or who prefer gentler hair care products.

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Are there any side effects of using DHT-blocking serums?

While DHT-blocking serums are generally considered safe and are well-tolerated by most people, they can sometimes cause side effects. These can range from mild to moderate and can include scalp irritation, redness, and itching. Some users may also experience increased hair shedding initially as the hair follicles transition from a resting phase to a growing phase. 

Furthermore, it's important to remember that everyone's skin and hair are different, so what works well for one person might not work as well for another.

As with any new product, it's a good idea to test a small amount on your skin first to check for any adverse reactions.

It's always wise to consult a healthcare professional or a dermatologist if you have any concerns or experience ongoing discomfort.

Read this: 15 Best Hair Growth Serums for Superior Hair Growth (2024)

An effective and safer alternative to dht blocking serums

Bio Pilixin Serum

Bio-Pilixin Activation Serum is a standout in the hair care market of 2024, offering a safer, plant-powered alternative to traditional DHT-blocking serums.

This potent formula addresses hair loss effectively while encouraging new hair growth, providing an excellent solution for those experiencing brittle and thinning hair, rejuvenating both your hair and scalp.

Bio Pilixin features Capilia Longa, a derivative of Curcuma longa stem cells.

This power-packed ingredient has demonstrated exceptional results in minimizing hair loss and enhancing hair density.

The serum also includes Niacinamide, known to boost sustained hair growth by enhancing scalp blood circulation and safeguarding hair follicles from damage.

One of the distinguishing ingredients in Bio Pilixin's formula is Vanillyl Butyl Ether, a mild warming agent that elevates scalp circulation.

This improvement in circulation ensures optimal delivery of nutrients and oxygen to hair follicles, which is crucial for healthy hair growth.

Suitable for both men and women, Bio-Pilixin leverages innovative, plant-powered ingredients to help combat hair loss and improve hair density.

This product's effectiveness has been backed by numerous positive user testimonials and the assurance of a 150 days money-back guarantee, reflecting the brand's confidence in their product's performance. 

Bio-Pilixin® Activation Serum | For Women
Bio-Pilixin® Activation Serum | For Women
Drug-free & clinically tested

Conclusion

In the quest to reclaim hair health, vitality, and density, DHT-blocking serums have emerged as a beacon of hope, particularly for those grappling with hair loss and thinning.

With scientifically-backed formulas and potent natural ingredients, these serums are an effective solution to significantly reduce hair loss, by neutralizing DHT - the primary culprit of hair damage.

The 2024 market is teeming with innovative, potent DHT-blocking serums, each promising a unique blend of benefits and proven effectiveness.

While PURA D'OR, MDhair, FOLIGAIN, Guyology labs, Re-Grow, and Propidren by Hairgenics are making waves in the hair care industry, the Bio-Pilixin Serum also stands out as a safer and plant-powered alternative for DHT blocking. 

Remember, consistency is key when using these products. It's also beneficial to incorporate ingredients like pumpkin seed oil that have been associated with hair health into your routine.

Also, don't forget to include beneficial lifestyle changes such as a balanced diet rich in nutrients and DHT-blocking elements like green tea for a holistic approach to hair health.

FAQs

Can I use DHT-blocking serums on curly hair?

Yes, you absolutely can. DHT-blocking serums are typically designed to work on all hair types, including curly hair. To enhance the effect and keep your curls healthy and shiny, you can also use a dedicated curly hair oil or serum alongside your DHT-blocking product.

Will DHT-blocking serums straighten my curly hair?

No, DHT-blocking serums are not designed to change the structure of your hair. They work to prevent hair loss and promote hair growth. They will not affect the curl pattern of your hair. If you want to maintain your curly hair's health and shine, consider using a curly hair oil or serum in addition to the DHT-blocking serum.

What should I look for in a curly hair oil/serum when using a DHT-blocking serum?

When using a curly hair oil or serum along with a DHT-blocking serum, look for products that are designed to enhance and define your curls while also providing essential moisture and frizz control. Ingredients such as argan oil, coconut oil, and jojoba oil can be beneficial. It's also essential to ensure that the product is free from sulfates, parabens, and other harsh chemicals, as they can strip your hair of its natural oils and exacerbate dryness and frizz.

Is DHT-blocking serum effective for both men and women?

Yes, DHT-blocking serums are designed to work for both men and women. Hair loss in both sexes is often linked to dihydrotestosterone (DHT), and these serums work by blocking the production of this hormone. However, the causes of hair loss can be complex and vary between individuals, so it's always a good idea to consult with a healthcare provider or dermatologist to understand the root cause of your hair loss before starting any new hair loss treatment.

References: 

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4171668/ 
  2. https://www.sciencedirect.com/science/article/pii/S0753332221000329 

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Dr Amy Revene M.B.B.S. graduated from the University of Sharjah in the United Arab Emirates. She is currently working as a General Physician at New Hope Medical Center. Amy has a passion for research and offers her expertise and opinions to help people in their quest to lead healthy, happy lives.