Can Lamotrigine Cause Hair Loss? Risks and Alternatives

Medically reviewedby Dr. Bilal Khan M.B.B.S.
WrittenbyDr. Edna Skopljak, M.D.
Last updated

Dr. Bilal Khan M.B.B.S earned his medical doctorate at Sindh Medical College, Jinnah Sindh Medical University in Karachi, Pakistan. In September 2023, he successfully passed the United States Medical Licensing Examination (USMLE), achieving certification to practice medicine internationally. Read more...

Lamotrigine, often known by the brand name Lamictal, is a medication primarily used to treat epilepsy and bipolar disorder. Like all medications, lamotrigine can have side effects. One side effect that concerns many is hair loss. This article will dive into the question: "Can lamotrigine cause hair loss?"

Can Lamotrigine Cause Hair Loss?

Yes, lamotrigine can potentially cause hair loss, although it's not a commonly reported side effect. The process of drug-induced hair loss is typically a condition called telogen effluvium, where the natural hair growth cycle is disrupted, leading to increased shedding and noticeable thinning. However, everyone reacts differently to medications, so not everyone taking lamotrigine will experience this side effect.

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Understanding Telogen Effluvium

Telogen effluvium is a form of temporary hair loss that typically occurs after stress, shock, or a traumatic event. Certain medications, including lamotrigine, can also trigger this condition. Normally, a majority of your hair is in the active growing phase, while a smaller proportion is in the resting, or telogen, phase. When telogen effluvium occurs, a larger proportion of hair moves into the telogen phase, leading to increased hair shedding and thinning.

Studies on Lamotrigine and Hair Loss

Some studies and reports have indicated a connection between lamotrigine and hair loss. In one case, hair loss was reported as a side effect of lamotrigine treatment in the American Journal of Psychiatry. However, it's important to remember that these instances are not widespread, and hair loss is not a listed side effect on the official lamotrigine medication guide.

Managing Lamotrigine-Induced Hair Loss

If you're experiencing hair loss while taking lamotrigine, it's important to consult with your healthcare provider. Adjusting the dosage or switching to another medication might be possible solutions. However, you should never stop taking any medication on your own due to potential side effects, as the risks, especially for individuals with bipolar disorder or epilepsy, are too great.

Conclusion

In conclusion, while lamotrigine can potentially cause hair loss, it's not a common side effect and doesn't affect everyone. If you're concerned about hair loss while taking lamotrigine, it's essential to consult with your healthcare provider to discuss your options and find the best solution for you.

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Dr. Edna Skopljak, M.D.

About the Writer

Edna Skopljak, MDUniversity of Ljubljana, Faculty of Medicine

Edna Skopljak, MD is a clinical doctor at the University Medical Center Ljubljana and a PhD candidate in Biomedicine at the University of Ljubljana. She combines clinical work with research and medical editing, bringing a clear, evidence-based lens to patient education. Previously, she held roles in the pharmaceutical sector (product management and chief medical officer) and served as a medical production editor for the journal Biomolecules and Biomedicine.

Dr. Skopljak’s publications span clinical topics, including urology and orthopedics. She has co-authored work affiliated with the Department of Orthopedic Surgery at University Medical Centre Ljubljana. She trained in medicine with early clinical experience in Slovenia, reflecting a long-standing focus on practical, patient-facing care.

She strictly follows our Editorial Standards: All medical statements are grounded in authoritative guidelines, FDA labels, and peer-reviewed studies, with clear distinction between approved treatments and adjunctive options.