Does Berberine Cause Hair Loss? Analyzing the Effects

WrittenbyDr. Edna Skopljak, M.D.
Last updated

Berberine is a plant alkaloid supplement used to help control blood sugar and cholesterol levels. But does it have any effect on hair health?

Table of content
1. Does berberine cause hair loss?

Does berberine cause hair loss?

While berberine is generally well-tolerated, a small percentage of individuals may experience temporary shedding when first starting supplementation due to its effects on metabolism.

Berberine's Mechanism

It improves cell signaling and hormone balance, both important for the hair follicle growth cycle.

Potential for Shedding

In rare cases, some report a brief 1-2 month telogen effluvium shed as the body adjusts to berberine's actions.

Genetic Influence

Those predisposed to hair loss or nutrient deficiencies could be more vulnerable to temporary shedding.

Typically Mild and Brief

Most episodes resolve independently without long-term hair loss as the body adapts to the supplement.

Risk Reduction

Starting with a low dose and slowly increasing, monitoring for shedding, and addressing deficiencies can help minimize potential issues.

Overall Benefits

Berberine's ability to balance metabolism supports scalp and hair health in the long run for most people.

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Dr. Edna Skopljak, M.D.

About the Writer

Edna Skopljak, MD — University of Ljubljana, Faculty of Medicine

Edna Skopljak, MD is a clinical doctor at the University Medical Center Ljubljana and a PhD candidate in Biomedicine at the University of Ljubljana. She combines clinical work with research and medical editing, bringing a clear, evidence-based lens to patient education. Previously, she held roles in the pharmaceutical sector (product management and chief medical officer) and served as a medical production editor for the journal Biomolecules and Biomedicine.

Dr. Skopljak’s publications span clinical topics, including urology and orthopedics. She has co-authored work affiliated with the Department of Orthopedic Surgery at University Medical Centre Ljubljana. She trained in medicine with early clinical experience in Slovenia, reflecting a long-standing focus on practical, patient-facing care.

She strictly follows our Editorial Standards: All medical statements are grounded in authoritative guidelines, FDA labels, and peer-reviewed studies, with clear distinction between approved treatments and adjunctive options.