Does Nettle Raise Estrogen?

WrittenbyDr. Edna Skopljak, M.D.
Last updated

Stinging nettle (Urtica dioica) is a herbaceous plant that has been used for centuries in traditional medicine for various purposes, including reducing inflammation, alleviating allergies, and supporting prostate health. However, there have been some concerns about its potential effects on hormone levels, particularly estrogen, which has led to questions about whether nettle raises estrogen levels in the body.

Does Nettle Raise Estrogen?

Based on current research, there is no conclusive evidence that stinging nettle directly raises estrogen levels in the body. However, some studies have suggested that nettle may have properties that could potentially influence estrogen metabolism and activity:

  • Some compounds found in nettle, such as lignans and isoflavones, are classified as phytoestrogens – plant-based compounds that can mimic or modulate the effects of estrogen in the body.
  • Animal studies have shown that nettle extracts may have estrogenic effects, although these effects were relatively weak compared to synthetic estrogens.
  • In vitro studies have demonstrated that nettle extracts may inhibit the activity of aromatase, an enzyme responsible for converting testosterone into estrogen. This could potentially lower estrogen levels indirectly.

It's important to note that the potential effects of nettle on estrogen levels and activity are still not fully understood, and the existing research has yielded mixed results.

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Factors Influencing Estrogen Levels

To better understand the potential impact of nettle on estrogen levels, it's crucial to consider the various factors that can influence estrogen production and metabolism in the body:

Age and Hormonal Changes

Estrogen levels naturally fluctuate throughout a person's life, with higher levels during reproductive years and a decline during menopause for women. The impact of nettle on estrogen may vary depending on an individual's age and hormonal status.

Body Composition and Metabolism

Factors such as body weight, body fat distribution, and overall metabolic health can influence estrogen production and clearance from the body. Individuals with different body compositions and metabolic profiles may respond differently to the potential estrogenic effects of nettle.

Existing Medical Conditions

Certain medical conditions, such as polycystic ovary syndrome (PCOS), endometriosis, or hormone-related cancers, may affect how the body processes and responds to estrogen. In these cases, the potential impact of nettle on estrogen levels should be carefully evaluated under medical supervision.

Potential Benefits and Risks

While the impact of nettle on estrogen levels remains inconclusive, there are potential benefits and risks associated with its use that should be considered:

Potential Benefits

  • Nettle may provide anti-inflammatory and antioxidant effects, which could be beneficial for various health conditions.
  • Some research suggests that nettle may help alleviate symptoms associated with benign prostatic hyperplasia (BPH) in men.
  • Nettle extracts have been studied for their potential in managing allergies and hay fever.

Potential Risks

  • Excessive consumption of nettle or high doses may cause gastrointestinal discomfort, fluid retention, or skin irritation.
  • Nettle may interact with certain medications, such as blood thinners, diuretics, or antidepressants.
  • Individuals with hormone-sensitive conditions or taking hormone therapy should exercise caution and consult with a healthcare professional before using nettle supplements.

Consulting a Healthcare Professional

If you have concerns about the potential effects of nettle on estrogen levels or are considering using nettle supplements, it's essential to consult with a qualified healthcare professional, such as a doctor, herbalist, or nutritionist. They can evaluate your individual health status, medication use, and any potential risks or contraindications associated with nettle consumption.

By understanding the current research on nettle and its potential impact on estrogen levels, as well as considering individual factors and consulting with a healthcare professional, you can make an informed decision about whether incorporating nettle into your routine is appropriate and safe for your specific needs.

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Dr. Edna Skopljak, M.D.

About the Writer

Edna Skopljak, MDUniversity of Ljubljana, Faculty of Medicine

Edna Skopljak, MD is a clinical doctor at the University Medical Center Ljubljana and a PhD candidate in Biomedicine at the University of Ljubljana. She combines clinical work with research and medical editing, bringing a clear, evidence-based lens to patient education. Previously, she held roles in the pharmaceutical sector (product management and chief medical officer) and served as a medical production editor for the journal Biomolecules and Biomedicine.

Dr. Skopljak’s publications span clinical topics, including urology and orthopedics. She has co-authored work affiliated with the Department of Orthopedic Surgery at University Medical Centre Ljubljana. She trained in medicine with early clinical experience in Slovenia, reflecting a long-standing focus on practical, patient-facing care.

She strictly follows our Editorial Standards: All medical statements are grounded in authoritative guidelines, FDA labels, and peer-reviewed studies, with clear distinction between approved treatments and adjunctive options.