Can Lamotrigine Cause Hair Loss? Risks and Alternatives

Medically reviewed by Dr. Bilal Khan M.B.B.S.
Written by Our Editorial Team
Last updated

Lamotrigine, often known by the brand name Lamictal, is a medication primarily used to treat epilepsy and bipolar disorder. Like all medications, lamotrigine can have side effects. One side effect that concerns many is hair loss. This article will dive into the question: "Can lamotrigine cause hair loss?"

Can Lamotrigine Cause Hair Loss?

Yes, lamotrigine can potentially cause hair loss, although it's not a commonly reported side effect. The process of drug-induced hair loss is typically a condition called telogen effluvium, where the natural hair growth cycle is disrupted, leading to increased shedding and noticeable thinning. However, everyone reacts differently to medications, so not everyone taking lamotrigine will experience this side effect.

Understanding Telogen Effluvium

Telogen effluvium is a form of temporary hair loss that typically occurs after stress, shock, or a traumatic event. Certain medications, including lamotrigine, can also trigger this condition. Normally, a majority of your hair is in the active growing phase, while a smaller proportion is in the resting, or telogen, phase. When telogen effluvium occurs, a larger proportion of hair moves into the telogen phase, leading to increased hair shedding and thinning.

Studies on Lamotrigine and Hair Loss

Some studies and reports have indicated a connection between lamotrigine and hair loss. In one case, hair loss was reported as a side effect of lamotrigine treatment in the American Journal of Psychiatry. However, it's important to remember that these instances are not widespread, and hair loss is not a listed side effect on the official lamotrigine medication guide.

Managing Lamotrigine-Induced Hair Loss

If you're experiencing hair loss while taking lamotrigine, it's important to consult with your healthcare provider. Adjusting the dosage or switching to another medication might be possible solutions. However, you should never stop taking any medication on your own due to potential side effects, as the risks, especially for individuals with bipolar disorder or epilepsy, are too great.


In conclusion, while lamotrigine can potentially cause hair loss, it's not a common side effect and doesn't affect everyone. If you're concerned about hair loss while taking lamotrigine, it's essential to consult with your healthcare provider to discuss your options and find the best solution for you.

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Dr. Bilal Khan M.B.B.S. graduated from the Jinnah Sindh University in Karachi. He'll take the official medical licensing program in the US (USMLE) in September 2023. Bilal has a passion for research and has extensively fact-check and medically review articles under his name to make sure you have the most accurate information.