Do Metformin Cause Hair Loss? Risks and Solutions

Medically reviewed by Dr. Bilal Khan M.B.B.S.
Written by Our Editorial Team
Last updated

Metformin is widely known as a prescription medication for treating type-2 diabetes. However, some users have raised concerns about its potential side effects, particularly hair loss. This article aims to shed light on the question: "Does Metformin cause hair loss?"

Does Metformin Cause Hair Loss?

No empirical evidence directly connects Metformin use to hair loss. However, some people have reported experiencing excessive hair loss after taking Metformin. It's worth noting that this could be attributed to the conditions requiring Metformin use, such as diabetes and PCOS, rather than the medication itself.

It must be mentioned that Metformin does not cause hair loss directly but, it may cause impaired absorption of vitamin B12 which can lead to anemia. Hair loss is secondary to anemia.

The Metformin-Hair Loss Connection

While Metformin itself may not trigger hair loss, it can contribute indirectly. Here's how:

  • Vitamin B-12 Deficiency: Long-term use of Metformin can lead to vitamin B-12 deficiency, a condition that can slow down hair growth and potentially cause hair loss.
  • Insulin Resistance and Metabolic Syndrome: Studies suggest an association between insulin resistance, metabolic syndrome (both of which Metformin treats) and hair loss from a condition called alopecia.
  • Diabetes: Diabetes can disrupt the hair growth process and cause you to lose more hair than usual. As Metformin is often prescribed for diabetes, this could explain why some users notice increased hair loss.

Addressing Metformin-Related Hair Loss

If you're experiencing hair loss while taking Metformin, there are steps you can take:

  • Consult your doctor: If you suspect Metformin is contributing to your hair loss, discuss your concerns with your healthcare provider.
  • Monitor vitamin levels: Regularly check your vitamin B-12 levels and consider supplements if necessary, under the guidance of your doctor.
  • Consider natural remedies: Simple home remedies can help slow the process of hair loss. However, these should be used as supportive measures and not as a replacement for medical advice.


In conclusion, while Metformin doesn't directly cause hair loss, certain conditions associated with its use, such as vitamin B-12 deficiency and diabetes, can contribute to hair loss. If you're using Metformin and experiencing hair loss, it's advisable to consult your doctor to identify the underlying cause and work out a solution.

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Dr. Bilal Khan M.B.B.S. graduated from the Jinnah Sindh University in Karachi. He'll take the official medical licensing program in the US (USMLE) in September 2023. Bilal has a passion for research and has extensively fact-check and medically review articles under his name to make sure you have the most accurate information.