Aminexil Vs Minoxidil: Which One Is Better For You?

Medically reviewedby Dr. Amy Revene M.B.B.S.
WrittenbyLuat Duong
Last updated

In the quest for luscious locks and a solution to thinning hair, two names consistently emerge in the spotlight: Aminexil and Minoxidil. 

These potent compounds long heralded for their potential in combatting hair loss, have stirred debates among experts and users alike. But which one truly stands out in effectiveness and safety? 

Delving deep into the science and testimonies behind Aminexil and Minoxidil, we endeavour to provide a comprehensive comparison to guide you in choosing the right remedy for your hair concerns. 

Stay with us as we explore the intricacies of Aminexil versus Minoxidil in hair care.

What is Aminexil?

aminexil vs minoxidil

Aminexil is a distinct molecule developed to counteract hair thinning and loss. Often found in hair care formulations, it seeks to maintain hair vitality by reinforcing hair fibres, preserving collagen around hair follicles, and potentially preventing premature hair shedding.

Originating from the family of minoxidil, Aminexil aims to reinforce hair fibres by preserving the collagen around the hair follicles, thus preventing them from becoming rigid and leading to premature hair loss. 

Many cosmetic companies integrate Aminexil into their hair serums and treatment solutions, positing it as a formidable solution to fortify hair roots and ensure longevity. 

While results can vary among individuals, promising evidence suggests its efficacy in hair regrowth and maintenance.

How does Aminexil work?

Aminexil targets the collagen around hair follicles, preventing it from hardening. This ensures better hair anchorage in the scalp, thus potentially reducing hair loss. Incorporated in various products, it revitalises hair fibres and promotes healthier, more resilient growth.

What are the benefits of using Aminexil?

  • Hair anchorage improvement: Aminexil enhances the anchoring of hair strands in the scalp, reducing hair shedding.
  • Collagen preservation: It prevents the hardening of collagen around hair follicles, ensuring the hair's structural integrity.
  • Promotion of hair growth: Some users report increased hair density and volume when consistently using products containing Aminexil.
  • Reduced hair thinning: Aminexil can address the early stages of hair thinning, ensuring thicker and healthier hair over time.
  • Suitable for sensitive scalps: Many formulations with Aminexil are designed to be gentle, making them ideal for sensitive scalps.
  • Enhanced hair vitality: Regular use can lead to more resilient, vibrant, and revitalised hair strands.
  • Complement to other treatments: Aminexil can be used alongside other hair treatments, amplifying overall benefits when appropriately combined.
  • Increased hair lifespan: By supporting the scalp environment and hair follicles, Aminexil can prolong the lifecycle of the hair.

What are the side effects of Aminexil?

  • Skin irritation: Some users may experience redness, itching, or scalp discomfort after applying Aminexil products.
  • Allergic reactions: Although rare, some individuals might be allergic to Aminexil, leading to symptoms like rashes or hives.
  • Dryness: Aminexil-containing products might cause some users' dryness or flakiness on the scalp.
  • Hair texture changes: Some people have reported temporary changes in hair texture, such as increased stiffness or coarseness.
  • Tingling sensation: A few users have reported a mild tingling or burning sensation upon application.
  • Temporary hair shedding: A small percentage of users might experience an initial increase in hair shedding, which usually subsides as the treatment progresses.
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What is Minoxidil?

aminexil vs minoxidil

Rogaine is formulated with minoxidil, a topical solution predominantly used to combat hair loss and promote regrowth. Initially developed as a medication for hypertension, its unforeseen ability to boost hair growth was soon discovered. 

Today, it's among the most popular over-the-counter solutions for hair thinning, offered in different strengths and favoured by individuals worldwide. 

Minoxidil operates by prolonging the growth phase of hair follicles, thus fostering more hair development and reducing hair thinning. Generally applied directly to the scalp twice daily, minoxidil has proven effective for both men and women. 

While it doesn't wholly reverse baldness, scientific studies affirm its capability to mitigate hair loss and, for some, encourage hair regrowth.

How does Minoxidil work?

Minoxidil, widely recognised by the brand name Rogaine, boosts blood flow to the areas it's applied to, predominantly the scalp. This increased circulation is believed to extend the anagen phase of the hair follicle cycle, the period dedicated to hair growth. 

Consequently, hair often appears more extended and denser. The therapy might also expand the size of hair follicles, enhancing hair volume. 

Through such processes, Minoxidil either slows down or stops hair shedding and, in some instances, stimulates hair regrowth for individuals grappling with patterned hair loss or thinning.

What are the benefits of using Minoxidil?

  • Promotes hair growth: Clinical studies affirm Minoxidil's ability to boost hair growth, especially in those with pattern baldness.
  • Reduces hair loss: Extending the hair follicles' growth stage effectively diminishes hair thinning and shedding. 
  • Suitable for both genders: Formulations of Minoxidil cater to both men and women, addressing diverse hair requirements. 
  • User-friendly application: Minoxidil is conveniently applied to the scalp, whether in foam or liquid form. 
  • Accessible without a prescription: Unlike specific hair treatments, Minoxidil is readily available over the counter in numerous locations. 
  • Enhances hair volume: Regular application augments hair thickness, enriching the overall hair aesthetic. 
  • Quick results: Many users observe encouraging hair growth outcomes within months of consistent application.
  • Complementary with other treatments: Minoxidil seamlessly integrates with various hair care products, amplifying its impact.
  • Reliable legacy: Minoxidil has solidified its credibility in hair care with years of research and widespread usage.

What are the side effects of Minoxidil?

  • Local Discomfort: One of the more frequent side effects, this can lead to itchiness, redness, peeling, or a sensation of burning/tingling at the application area. The tingling might be due to the enhanced circulation caused by the drug.
  • Allergic Contact Dermatitis: Some users might undergo an allergic reaction, showcasing symptoms similar to local discomfort, encompassing itchiness, inflammation, and desquamation.
  • Anaphylactic Reaction: A seldom but allergic severe response, it can manifest symptoms such as welts, an extensive body rash, nausea, regurgitation, and swelling in areas like the lips, tongue, or throat. Encountering these signs warrants an immediate halt in product usage and urgent medical intervention.
  • Initial Hair Shedding: Commonly observed at the onset of the treatment, this phase is occasionally termed 'minoxidil shedding' or 'dread shed.' This process occurs as dormant hair follicles discard their present hair to pave the way for newer, healthier strands.

An effective alternative to Aminexil and Minoxidil

aminexil vs minoxidil

Scandinavian Biolabs offers its Bio-Pilixin® Serum, a formula crafted with the aim of supporting hair growth.

Utilising state-of-the-art stem cell techniques, the serum brims with plant-derived growth factors to nourish hair roots and promote vigorous hair sprouting from the foundation. Clinical studies indicate observable differences in 45 days.

Rather than boasting unsubstantiated benefits, the Bio-Pilixin® Serum proves its mettle—In clinical trials, 93% of participants noted positive effects.

Every ingredient in this revolutionary serum adheres to stringent quality benchmarks and is selected following meticulous scientific scrutiny. 

A standout ingredient, Capilia Longa—sourced from the stem cells of Curcuma longa—has clinically demonstrated its ability to slash hair loss rates by an impressive 89–90% and amplify hair thickness by over half. 

Complementing this is Niacinamide, which bolsters blood flow and shields hair roots from environmental aggressors and sun exposure. 

With its compelling concoction of prime ingredients, the Bio-Pilixin® Serum stands out as a game-changer in hair wellness. 

Plus, We offer a money-back guarantee for those who are not satisfied after 150 days.

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Aminexil vs. Minoxidil: What are the differences?

Aminexil and Minoxidil are prominent treatments in the battle against hair loss, but they hail from different chemical backgrounds and have distinct mechanisms of action. While their end goal is similar, they approach hair regrowth and maintenance from slightly different angles.

Chemical structure

Aminexil is derived from Minoxidil but has a distinct molecular structure, which can influence its interaction with hair follicles.

Mechanism of action

Minoxidil primarily works by enlarging miniaturised follicles and increasing blood flow. Aminexil, on the other hand, focuses on preserving the collagen around hair follicles to prevent hardening.

Formulation availability

While Minoxidil is more commonly found in over-the-counter hair loss products, Aminexil is typically present in speciality hair care products, particularly in European markets.

Duration of efficacy

While both compounds require a consistent application for optimal results, the time frame for noticeable results might vary.

Aminexil vs. Minoxidil: Which one is better for you?

Aminexil and Minoxidil are both effective hair loss treatments, each offering unique benefits. Minoxidil, widely recognised and available, primarily enlarges miniaturised follicles and enhances blood flow. Aminexil, often found in speciality products, preserves collagen around hair follicles to prevent hardening. 

The best choice depends on individual preferences, specific hair concerns, and potential side effects. Consulting with a dermatologist or hair care specialist can provide tailored recommendations.


Aminexil and Minoxidil have carved out their niches in the expansive world of hair care solutions. Each offers its unique mechanism of action, targeting hair loss and promoting regrowth from different angles. 

While Minoxidil has a longer-standing reputation and broader availability, Aminexil has been making waves in specific markets, particularly for its focus on collagen preservation. 

Ultimately, the decision between the two boils down to individual needs, preferences, and the specific nature of one's hair loss condition. 

As with all treatments, seeking professional advice is always the best approach to ensure optimal results and safety.



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Luat Duong

Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.