Minoxidil and Finasteride Topical Solution: Benefits, Usage, and Side Effects

Medically reviewed by Dr. Amy Revene M.B.B.S.
Written by Our Editorial Team
Last updated

Are you looking for an effective solution to combat hair loss? Minoxidil and Finasteride topical solution could be the answer. This powerful combination has been proven to help in regrowing hair and preventing further loss. 

In this article, we will delve into the benefits, application methods, and potential side effects of using the minoxidil and finasteride topical solution for hair growth, offering a detailed guide for anyone considering this treatment for male pattern hair loss.

What is minoxidil, and how does it work?

minoxidil and finasteride topical solution

Topical minoxidil, a vasodilator medication initially developed for high blood pressure, was unexpectedly found to stimulate hair growth in hair follicles, making it an FDA-approved treatment for androgenetic alopecia. 

Its primary mechanism is to boost blood flow to the hair follicles, enhancing hair density and growth, which may slow the progression of male pattern baldness.

While the exact science behind how minoxidil promotes hair regrowth remains partially understood, it's believed to work by opening potassium channels and thereby widening blood vessels in the scalp. 

This increased blood flow delivers more oxygen, blood, and nutrients to hair follicles, which can revitalize shrunken follicles, making them larger and restoring their ability to produce healthy hair. Furthermore, topical minoxidil is believed to prolong the anagen phase of the hair growth cycle, resulting in longer and a noticeable improvement in hair density.

What is finasteride and how does it work?

finasteride to treat hair loss

Oral finasteride, a medication known for its effectiveness in treating androgenetic alopecia, specifically targets male pattern baldness by reducing DHT levels. As a 5-alpha-reductase inhibitor, finasteride's primary mechanism involves the suppression of dihydrotestosterone (DHT) production, a hormone closely linked to hair loss.

By reducing DHT levels in the scalp, oral finasteride slows down hair follicle miniaturization, a common cause of male pattern hair loss, and effectively reduces overall hair loss.

Upon regular intake, typically a 1mg daily dose, finasteride can significantly reduce DHT levels, thereby decelerating hair loss and potentially reversing the trend by promoting the thickening of miniaturized hair follicles. 

The effectiveness of finasteride varies among individuals, with many users experiencing a halt in hair loss progression and a noticeable increase in hair count, especially in the crown and mid-scalp areas.

What are minoxidil and finasteride topical solution?

The topical finasteride and minoxidil solution represents a dual-action treatment for hair loss, combining the benefits of both to target androgenetic alopecia more effectively. 

This innovative topical finasteride and minoxidil solution is crafted to combat male pattern hair loss by both stimulating hair growth and preventing hair follicle miniaturization through a reduction in DHT levels. 

The synergy of minoxidil and finasteride in a single topical formulation offers a convenient and potentially more effective approach to hair loss treatment. Minoxidil widens blood vessels and improves blood flow to hair follicles, supporting hair regrowth and revitalization. 

Meanwhile, finasteride targets the hormonal aspect of hair loss by inhibiting the enzyme responsible for converting testosterone into DHT, the hormone implicated in the miniaturization of hair follicles and hair loss. 

By combining these two mechanisms of action, the minoxidil and finasteride topical solution aims to provide a more comprehensive treatment strategy, potentially enhancing the outcomes for individuals dealing with androgenetic alopecia. 

This dual-action treatment, combining topical finasteride and minoxidil, may be particularly advantageous for those seeking enhanced results beyond what single-ingredient products can provide.

Benefits of minoxidil and finasteride topical solution


Minoxidil and finasteride topical solution combines the hair growth-stimulating effects of minoxidil with the DHT-reducing properties of finasteride, offering a potent dual-action approach to treating androgenetic alopecia (male pattern baldness). This combined treatment can significantly enhance hair regrowth and slow down hair loss.

Some of the key benefits include:

  • Enhanced hair regrowth: The solution stimulates hair follicles to promote new growth and thicken existing hair.
  • Reduced hair loss: By lowering DHT levels, it helps prevent further hair follicle miniaturization and hair loss.
  • Convenient application: A single topical product simplifies the treatment regimen.
  • Potentially improved efficacy: Combining two proven hair loss treatments may offer better results than using either product alone.
  • Suitable for early and advanced stages: Effective in various stages of hair loss, providing benefits for a wide range of users.

    What causes hair loss?

    Hair loss can result from a variety of factors, ranging from genetic predispositions to lifestyle and environmental influences. It's a condition that affects both men and women and can significantly impact self-esteem and quality of life.

    Some common causes of hair loss include:

    • Genetic factors: The most common cause, known as androgenetic alopecia, or male/female pattern baldness.
    • Hormonal changes: Including those due to pregnancy, childbirth, menopause, or thyroid problems.
    • Medical conditions: Such as alopecia areata (an autoimmune disease that attacks hair follicles), scalp infections like ringworm, and trichotillomania (a hair-pulling disorder).
    • Medications: Certain drugs used for cancer, arthritis, depression, heart problems, gout, and high blood pressure can cause hair loss.
    • Nutritional deficiencies: Lack of essential nutrients like iron, protein, and vitamins can lead to hair thinning and loss.
    • Stress: Both physical and emotional stress can trigger temporary hair loss.
    • Hairstyles and treatments: Excessive styling and hair treatments can contribute to hair loss by damaging the hair follicles.

      Minoxidil and finasteride topical solution dosage

      The dosage of minoxidil and finasteride topical solution typically depends on the concentration of the active ingredients and the specific product formulation. It's crucial to follow the prescribing information or a healthcare provider's directions for use to ensure safety and effectiveness.

      Minoxidil topical solution dosage

      Minoxidil is commonly available in 2% and 5% concentrations for topical application. The recommended dosage is usually 1 ml of solution applied twice daily to the scalp, specifically in the areas of hair thinning or loss.

      Finasteride topical solution dosage

      Finasteride topical solutions can vary in concentration, but 0.1% to 0.25% is common. The typical application is 1 ml once daily to the scalp, focusing on areas experiencing hair loss.

      What are the side effects of minoxidil and finasteride topical solution

      Minoxidil and Finasteride, while effective for treating hair loss, may also have side effects. Understanding these side effects can help individuals make informed decisions about their hair loss treatments. Here's a brief overview of the potential side effects of Minoxidil and Finasteride:


      • Scalp irritation: Minoxidil may cause itching, redness, or dryness on the scalp.
      • Unwanted hair growth: In some cases, Minoxidil may cause hair growth on unintended areas, such as the face.
      • Dizziness: Some users may experience dizziness or light-headedness due to a drop in blood pressure.
      • Rapid heartbeat: Minoxidil can cause an increased heart rate in rare instances.


        • Sexual side effects: One of the side effects of finasteride, whether used topically or orally, may include a decreased libido, erectile dysfunction, or changes in ejaculation.
        • Breast tenderness or enlargement: Some men may experience breast changes while using Finasteride.
        • Depression: Use of finasteride, whether topical or oral, has been associated with an increased risk of depression in some individuals, alongside other potential side effects like erectile dysfunction.
        • Allergic reactions: Rarely, individuals may experience an allergic reaction to Finasteride, which could include symptoms like rash, itching, or swelling.

          A better alternative to minoxidil and finasteride topical solution


          hair growth serum

          Bio-Pilixin Serum offers an innovative alternative to traditional hair loss treatments such as minoxidil and finasteride topical solutions.

          Developed with advanced stem cell technology and enriched with plant growth factors, this serum is designed to nurture hair follicles and stimulate hair growth.

          Clinical tests have demonstrated noticeable results in reducing hair loss and encouraging new growth within just 45 days. 

          A key component, Capilia Longa, has shown up to an 89% reduction in hair loss and a 52% improvement in hair density in studies, with 93% of participants satisfied with their outcomes.

          Additionally, the serum is formulated with Niacinamide to strengthen hair by stimulating keratin production and Vanillyl Butyl Ether to improve scalp blood flow through a warming, tingling sensation. 

          This blend of natural compounds and innovative ingredients makes Bio-Pilixin Serum a potent and promising solution for those seeking effective hair loss treatment without relying on conventional chemical-based products. 

          Bio-Pilixin® Activation Serum | For Men
          Bio-Pilixin® Activation Serum | For Men
          Drug-free & clinically tested


          While Minoxidil and Finasteride topical solution has been a go-to treatment for androgenetic alopecia, offering significant benefits in hair regrowth and reduction of hair loss, it's not without its side effects. 

          For those seeking an alternative that leverages natural ingredients and cutting-edge technology, Bio-Pilixin Serum emerges as a compelling option.

          With its innovative formula that includes Capilia Longa, Niacinamide, and Vanillyl Butyl Ether, Bio-Pilixin Serum has shown promising clinical results in reducing hair loss and improving hair density, all while providing a satisfying user experience. 

          This serum represents a blend of nature and science, offering a new hope for individuals looking to combat hair loss with a treatment that is both effective and gentle.

          Whether you're facing the early signs of hair thinning or dealing with more advanced stages of hair loss, the key is to explore your options and choose a treatment that aligns with your needs and preferences, potentially considering the natural and innovative approach offered by Bio-Pilixin Serum.


          What are the side effects of applying minoxidil?

          Topical minoxidil, available as a foam or liquid solution, is mostly well-tolerated. However, it may cause temporary hair shedding, scalp irritation, changes in hair texture, and in rare cases, a fast heartbeat. Using a low-dose tablet form of minoxidil can help avoid some of these side effects.

          Does finasteride permanently regrow hair?

          Finasteride can increase hair counts during the first year of use and slow down the progression of male pattern hair loss thereafter. It's crucial to note that finasteride does not permanently stop or reverse male pattern hair loss.

          Is topical finasteride safe to use?

          Yes, topical finasteride is generally safe for treating hair loss. According to the FDA, finasteride does not interact with other drugs, making it safe for both oral and topical use in conjunction with other medications. 


          1. https://pubmed.ncbi.nlm.nih.gov/15316165/ 

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            Dr Amy Revene M.B.B.S. graduated from the University of Sharjah in the United Arab Emirates. She is currently working as a General Physician at New Hope Medical Center. Amy has a passion for research and offers her expertise and opinions to help people in their quest to lead healthy, happy lives.