Topical DHT Blockers: Everything You Need To Know

Medically reviewedby Dr. Zac Hyde M.D.
WrittenbyLuat Duong
Last updated

DHT is a byproduct of testosterone metabolism that interferes with the normal growth cycle of hair follicles. High concentrations of DHT make up the hallmark of a chronic condition known as androgenic alopecia.

In a previous article, we listed a number of methods that answers the question "how to remove DHT from scalp". This includes medications, light therapy, and dietary choices.

In this article, we will cover the most common topical DHT blockers and their mechanism of action.

    Are there better options to topical DHT blocker?

    Before you opt for a DHT blocker, it's wise to evaluate the risks:

    • DHT blockers, as the name suggests, block DHT which can cause unwanted side effects.
    • Topical DHT blockers are not always effective, and they are also quite expensive.
    • They're not FDA-approved, and many don't have sufficient testing.

    It doesn't really make sense when there's a safe, effective and affordable alternative on the market.

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    How to choose the best topical dht blocker?

    Now that you understand the importance of a topical DHT blocker, you need to learn how to choose a good brand. Unfortunately, many companies claim that their product is effective at blocking DHT without any solid scientific evidence.

    To summarize, here are the ingredients that you must find in any topical DHT blocker before making a purchase:


    This medication is common in topical DHT blockers. However, make sure you are getting a reputable brand. Some companies would throw the label of having finasteride in their products while they only contain traces. There are also many alternative to finasteride. Read more in our journal!

    Saw palmetto

    This is an extract from berries of a palm found in southeastern United States. Topical products that contain this ingredient may lower DHT levels, which promotes hair regrowth. In a 2020 review, researchers found some effect of saw palmetto on hair regrowth.

    Pumpkin seed oil

    Another important ingredient to look for in topical DHT blockers is pumpkin seed oil. Scientists believe that this oil blocks the action of alpha-5 reductase, which is the enzyme that converts testosterone to DHT.


    As part of the azole family, this compound is very effective against fungi and also exerts anti-inflammatory actions. In a 2011 study, researchers found that 15 individuals with alopecia experienced hair regrowth after applying ketoconazole to their scalp.

    There you have it! Before buying any topical DHT blocker, read the label carefully and make sure it contains at least one of these ingredients.

    The best topical DHT blockers on the market

    There are many topical DHT blockers on the market. However, not all of them are created equal. With so many options, it can be difficult to find the best topical DHT blockers that work for your needs.

    Here are the best topical DHT blockers and which ones are worth your time and money.

    Ultrax Labs Hair Surge

    Ultrax Labs Hair Surge

    This product contains ketoconazole, saw palmetto, peppermint oil, and caffeine. This unique combination blocks DHT action at numerous levels.

    Keeps Thickening Shampoo

    The company Keeps offers several hair loss-fighting products, including their thickening shampoo. The ingredients found in this shampoo include saw palmetto, biotin, caffeine, and green tea.

    PURA D’OR Original Gold Label Anti-Hair Thinning Shampoo

    Also rich in saw palmetto, this shampoo is effective at blocking DHT activity.

    Pure Biology RevivaHair Growth Stimulating & Anti Hair Loss Shampoo

    Another shampoo with a unique blend that blocks the action of DHT levels. Thousands of customers are satisfied with this product.

    Takeaway message

    Applying a topical DHT blocker to your scalp may aid with hair regrowth when the product is of high quality. Do not try these products if you have any concurrent dermatological conditions.

    We hope that this article managed to shed some light on the various types of topical DHT blockers and how they could potentially help with androgenic alopecia.

    For tailored medical advice, make sure to speak with your primary care physician or dermatologist about the effectiveness and safety of topical DHT blockers.



    Luat Duong

    Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.