Serioxyl Vs Minoxidil: Which Is Better For Hair Growth In 2024?

Medically reviewedby Dr. Amy Revene M.B.B.S.
WrittenbyLuat Duong
Last updated

Wondering whether to choose Serioxyl or Minoxidil for your hair loss treatment?

This article delves into the differences between Serioxyl and Minoxidil, helping you understand which solution might be more effective for your specific hair growth needs.

Explore their mechanisms, benefits, and user experiences to make an informed decision.

What is Serioxyl?

serioxyl vs minoxidil

Serioxyl is a hair care range designed to combat thinning hair and hair loss. Developed by L'Oréal Professionnel, it incorporates targeted technologies with ingredients like Stemoxydine and Neohesperidin to promote denser, thicker hair.

Serioxyl, a brainchild of L'Oréal Professionnel, is specially curated to address the woes of thinning hair. Recognizing the struggles and self-consciousness that thinning hair can bring, this range offers products catering to natural and coloured hair. 

From shampoos to conditioners and serums, Serioxyl is anchored in cutting-edge research to bring back the confidence associated with a fuller mane.

How does Serioxyl work?

Serioxyl employs Stemoxydine, which aims to recreate a suitable environment for hair follicles, and Neohesperidin, known for its protective effects on the scalp. Together, these ingredients work to promote a denser hair appearance.

Stemoxydine, a patented molecule by L'Oréal, is one of the key players in Serioxyl's efficacy. By mimicking the environment ideal for hair follicles, it seeks to rekindle dormant ones. 

Neohesperidin, on the other hand, is renowned for its antioxidant properties, working diligently to safeguard the scalp against daily aggressors. 

When these components work in synergy, they pave the way for a fuller, denser hair appearance, transforming thin strands into a lavish crown.

Key Ingredients in Serioxyl:

  • Stemoxydine: An active ingredient that aims to recreate an optimal environment for hair follicles, potentially reawakening dormant ones.
  • Neohesperidin: A known antioxidant, it provides protective effects on the scalp and might contribute to a healthier scalp environment.
  • GlucoBoost: Acts on the hair roots, providing nutrients and energy necessary for hair growth.
  • Incell: Works on the hair fibre, aiming to provide strength and flexibility.

Are there any side effects of Serioxyl?

Serioxyl may cause certain side effects in some users, including scalp sensitivity and potential allergic reactions. Here are the details:

  • Scalp sensitivity or irritation in some users.
  • Mild itching or tingling sensation.
  • Unusual hair texture or feel after application.
  • Potential allergic reactions in rare cases. Always patch-test before full application.
  • Temporary changes in hair volume may not suit everyone's preference.
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What is Minoxidil?

serioxyl vs minoxidil

Minoxidil, an active ingredient in Rogaine, is a topical solution widely recognized for addressing hair loss and promoting hair regrowth. 

Originally developed as an antihypertensive medication, an unexpected side effect emerged: hair growth. Today, it's among the top over-the-counter hair loss treatments, available in diverse concentrations and trusted by users worldwide. Minoxidil operates by prolonging the hair follicles' growth phase, fostering the growth of more hair strands and slowing hair loss. 

It has proven effective for both genders when applied directly to the scalp twice daily. While it doesn't wholly reverse baldness, its potency in stalling hair loss progression and even boosting hair regrowth in some instances is backed by science.

How does Minoxidil work?

Often sold under the name Rogaine, Minoxidil boosts blood flow to the application areas, predominantly the scalp. This process is believed to extend the anagen phase of the hair follicle cycle, which is crucial for hair growth. 

Consequently, hair often grows longer and denser. The solution also amplifies the size of hair follicles, further enhancing hair density. Through these actions, Minoxidil reduces hair loss and, in several cases, rejuvenates hair growth in individuals grappling with pattern baldness or hair thinning.

Key Ingredients in Minoxidil

The fundamental active component in Minoxidil-oriented products, including Rogaine, is Minoxidil itself, commonly found in concentrations of 2% or 5%. This ingredient is the driving force behind hair regrowth. Besides the main active ingredient, these products integrate additional elements that function as stabilizers, preservatives, or amplifiers, such as:

  • Alcohol: Acts as a solvent, ensuring smoother application.
  • Propylene Glycol: Assists in enhancing skin absorption.
  • Purified Water: Serves as the foundational medium for the solution.

Foam versions of Minoxidil products might omit propylene glycol to minimize potential skin irritation, but they still incorporate akin stabilizers and solvents.

Are there any side effects of Minoxidil?

Here are potential side effects linked with Minoxidil, irrespective of its brand:

  • Localized skin irritation: This commonly reported side effect includes symptoms like itchiness, redness, peeling, or sensations of tingling or burning. The tingling is likely a result of the elevated blood flow stimulated by the drug.
  • Contact dermatitis: Some users may exhibit allergic skin reactions, often displaying symptoms resembling localized irritation, which includes itchiness, redness, and skin flaking.
  • Anaphylaxis: Although uncommon, a severe allergic reaction might manifest with indicators like hives, an extensive rash, nausea, vomiting, and swelling in the lips, tongue, or throat. If these symptoms appear, stopping using the product and seeking urgent medical assistance is vital.
  • Initial hair loss: Often noticed at the beginning of the regimen, this is occasionally referred to as 'Minoxidil shedding' or the 'dread shed.' It occurs as resting hair follicles release weaker strands, paving the path for the emergence of newer, more robust hair.

An effective alternative to Serioxyl and Minoxidil

alternative to serioxyl and minoxidil

The Bio-Pilixin® Serum by Scandinavian Biolabs presents a groundbreaking solution engineered to help combat hair loss while boosting hair growth and thickness. 

Utilizing advanced stem cell technology, this distinctive serum is infused with numerous plant growth factors that revitalize hair follicles, propelling strong hair growth from the base. Clinical evaluations underscore its effectiveness, showcasing discernible progress in 45 days. 

The Bio-Pilixin® Serum isn't just about lofty promises; 93% of clinical study participants vouched for its positive outcomes. Designed for everyday use, this botanical serum supplies vital nutrients and invigoration your hair needs to thrive. 

Each ingredient in this pioneering serum adheres to the pinnacle of quality benchmarks, selected after meticulous scientific scrutiny. 

Capilia Longa, derived from the stem cells of Curcuma longa, has been scientifically validated to diminish hair loss by an impressive 89–90% and amplify hair density by 52%. 

Complementing this is Niacinamide, which bolsters the serum by enhancing blood flow and shielding hair follicles from premature damage due to environmental toxins and UV exposure. 

Plus, our faith in our serum's prowess is such that we extend a money-back guarantee if results after 150 days don't meet your expectations.

Bio-Pilixin® Activation Serum | For Men
Bio-Pilixin® Activation Serum | For Men
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Serioxyl Vs Minoxidil: What are the differences?

Serioxyl and Minoxidil are reputable names in the hair loss treatment sector. Still, they differ in formulation, mechanism of action, and origin. Let's delve into their distinct attributes.

Origin and development

Serioxyl is a hair care range designed by L'Oréal Professionnel to counter thinning hair using targeted technologies and ingredients. 

Initially developed as an antihypertensive medication, Minoxidil was discovered to have hair growth-promoting side effects, leading to its widespread use as a topical hair loss remedy.

Mechanism of action

Serioxyl employs ingredients like Stemoxydine and Neohesperidin to create a favourable environment for hair follicles and promote denser hair. 

Conversely, Minoxidil boosts blood circulation to the scalp, prolonging the anagen phase of hair follicles, which fosters hair growth.

Application and usage

While Serioxyl is a range encompassing various products like shampoos, conditioners, and serums, Minoxidil is typically a topical solution applied directly to the scalp twice daily.

Serioxyl Vs Minoxidil: Which one is better for you?

If one seeks a comprehensive hair care regimen with multiple products, Serioxyl might be preferable. However, for those who want a proven topical solution with extensive research backing its hair growth properties, Minoxidil might be the go-to choice. 

Always consult with a dermatologist or trichologist before making a decision.


Serioxyl and Minoxidil stand as powerful contenders in hair growth treatments, each boasting unique advantages. 

Serioxyl offers a holistic approach with its range, while Minoxidil provides a direct, scientifically-backed solution.

Incorporating products like the Bio-Pilixin® Serum by Scandinavian Biolabs, which harnesses advanced stem cell technology, can further elevate hair care routines. 

The final choice should align with individual needs and be made under professional guidance.



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Luat Duong

Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.