Best 9 Hair Treatment Serums To Stop Frizz And Get Radiant Locks in 2025

Medically reviewedby Dr. Amy Revene M.B.B.S.
WrittenbyLuat Duong
Last updated

Frizzy hair can be a constant battle, but the right hair treatment serum can work wonders to smooth, hydrate, and add shine.

These serums are formulated with nourishing ingredients like argan oil, silicone, and vitamin E, which help to seal moisture, reduce frizz, and promote radiant, shiny hair. 

Whether you have curly, straight, or wavy hair, a good serum can provide the perfect solution for achieving that sleek, frizz-free look.

In this guide, we’ve carefully curated the 9 best hair treatment serums to stop frizz and give you radiant locks.

These products are designed to smooth flyaways, enhance shine, and protect your hair from environmental damage, leaving it looking healthy, silky, and manageable.

What is a hair treatment serum?

A hair treatment serum is a liquid product designed to improve hair health and manageability. It contains active ingredients that nourish, protect, and add shine.

Serums can address various concerns, such as taming frizz, reducing split ends, promoting growth, and restoring shine. Ingredients like argan oil, jojoba oil, and silicones help condition, protect, and smooth the hair.

Why you can trust Scandinavian Biolabs?
TrichoAI Hair Loss Analysis
Our free, anonymous and dermatologist-developed AI analyzes your hair loss in 30 seconds, suggesting personalized solutions to combat thinning. Understanding your hair condition has never been easier.
Yes, I want to fix hair loss

How does hair treatment serum work?

Hair serums work by penetrating the hair shaft, delivering active ingredients that nourish, protect, and enhance hair health. They address specific needs, like hydration, protection from environmental stress, or strengthening hair. 

Many serums smooth the cuticles, adding shine and reducing frizz by coating the hair with ingredients like silicones.

9 Best Hair Treatment Serums

Unveiling the best hair treatment serums, we present an expertly curated list that promises to breathe life back into your strands. 

🔹 Best for Hair Growth: Bio Pilixin Serum – A powerful serum designed to stimulate hair follicles, promoting growth and reducing hair thinning with its nourishing formula.

🔹 Best for Bond Repair: Olaplex No. 9 Bond Protector Nourishing Hair Serum – This serum protects and nourishes while repairing damaged hair bonds, leaving the hair healthier and stronger.

🔹 Best for Density: The Ordinary Multi-Peptide Serum for Hair Density – A highly effective serum that targets thinning hair and encourages a fuller, denser appearance by boosting scalp health.

🔹 Best for Nourishment and Soothing: Laaayed Nourishing & Soothing Serum – A blend of nourishing ingredients that hydrate, calm, and restore balance to the scalp and hair.

🔹 Best for Shine: Sachajuan Shine Serum – This serum provides instant shine, smoothness, and a polished look to the hair without being greasy or heavy.

🔹 Best for Anti-Aging: Alterna Caviar Anti-Aging Restructuring Bond Repair Serum – A luxurious serum designed to repair and rebuild hair bonds, improving the overall texture and strength of aging hair.

🔹 Best for Signature Shine: Goldie Locks Signature Serum – Offers a smooth, glossy finish while treating and protecting the hair with its unique blend of ingredients.

🔹 Best for Scalp Health: Nécessaire The Scalp Serum – Focuses on scalp health by improving circulation and nourishing hair follicles, resulting in healthier hair growth.

🔹 Best for Hair Regrowth: Vegamour GRO Hair Serum – A plant-based, vegan serum that promotes thicker, fuller hair by nourishing the scalp and encouraging natural hair regrowth.

 

1. Bio Pilixin Serum

test winner hair treatment serum to stop frizz

Earning a top spot in our 2025 round-up of the best hair treatment serums, Bio Pilixin Serum has carved a niche for itself with its promising all-natural and potent formula. 

This serum is formulated with ingredients that aim to support the health of your hair and offer a natural approach for those experiencing brittle, thinning hair or hair fall.

At the heart of Bio Pilixin Serum's effectiveness is its innovative blend of ingredients.

One key ingredient is Capilia Longa, a derivative of Curcuma longa stem cells, which has been researched for its potential to support hair health and density.

Another key ingredient is Niacinamide, which is known for its role in supporting scalp circulation and thus potentially aiding in nutrient delivery to hair follicles and overall protection of the hair growth cycle.

A unique aspect of this formula includes Vanillyl Butyl Ether, a mild warming agent that aims to support scalp blood circulation, which could assist in nutrient and oxygen delivery to hair follicles.

With a carefully selected blend of ingredients and positive user feedback, Bio Pilixin Serum offers an approach for those looking to support the health of their hair.

What sets Bio Pilixin Serum apart from the crowd is its confident 150 days money-back guarantee. 

The brand stands by its product and its effectiveness, allowing customers to try it for an extended period, which is typically enough to see tangible results. 

Bio-Pilixin Activation Serum | For Women
Bio-Pilixin Activation Serum | For Women
Our star serum – nurtures hair follicle growth

2. Olaplex No. 9 Bond Protector Nourishing Hair Serum

hair treatment serum

Olaplex's No.9 Serum is the epitome of a multitasking hair serum. This ingenious product ticks all the boxes by hydrating, protecting, and adding shine for all hair types. 

It forms a protective shield against pollution for up to 48 hours, tames static and tangles, and guards your hair against heat damage. 

A few drops applied to damp or dry hair deliver a silky, lightweight finish without the use of silicones. 

Reviewers have raved about its ability to enhance the appearance of health and silkiness, even on damaged hair, and its power to control flyaways throughout the day. 

This serum has undoubtedly earned its place at the top of our list.

Shop now

3. The Ordinary Multi-Peptide Serum for Hair Density

Best hair treatment serum

The Ordinary's Multi-Peptide Serum is a savior for those yearning for thicker, fuller, and denser hair. 

This product works its magic regardless of the cause of hair loss, whether it's due to alopecia, post-pregnancy, or overplucking.  

Simply apply it to your scalp before bedtime, and you'll start noticing fuller hair in just a few months. The serum's inclusivity also stands out, as it caters to all hair types and textures.

Shop now

4. Laaayed Nourishing & Soothing Serum

best hair treatment serum

The Laaayed Nourishing & Soothing Serum is a brainchild of the founder of PuffCuff, a popular hair clamp brand for thick, curly hair. 

This serum specifically targets hair and scalp dryness and helps define your curls, twists, or braids. 

Whether applied to wet hair post-detangling or dry hair for hydration, it effectively seals in moisture, improving the overall health of your hair and scalp.

Shop now

5. Sachajuan Shine Serum

hair treatment serum

Despite its petite size, the Sachajuan Shine Serum delivers big on promises. 

This compact powerhouse offers a protective, shiny finish to your hair while sealing split ends and preventing further damage

Its lightweight formula, which is also TSA-friendly, quickly absorbs into your hair without leaving behind any residue or weighing it down.

Shop now

6. Alterna Caviar Anti-Aging Restructuring Bond Repair Serum

Alterna Caviar Anti-Aging Restructuring Bond Repair Serum

Alterna's 3-In-1 Sealing Serum is the perfect example of a multitasking hair serum. It repairs damaged hair, boosts softness and shine, and shields against heat styling in one neat package. 

Its unique caviar extract aids in sealing hair cuticles to safeguard damaged hair. 

This versatile serum is lightweight and an excellent base for layering heavier products, making it an ideal choice for all hair types.

Shop now

7. Goldie Locks Signature Serum

hair treatment serum

For those who prioritize convenience and travel-friendly hair care, Goldie Locks Signature Serum is a must-have. 

It's designed to combat the negative effects of sunshine, chlorine, humidity, or sea salt on your hair while you're on the go. 

This fast-absorbing serum ensures your hair stays shiny and frizz-free, regardless of your destination. 

The secure cap and travel-sized packaging offer a worry-free solution to hair care on the move. 

Plus, the brand includes two complimentary hair care samples with every purchase, further enhancing its appeal.

Shop now

8. Nécessaire The Scalp Serum

best hair treatment serum

In the realm of hair care, maintaining a healthy scalp is often overlooked, despite its critical role in hair health. This is where Nécessaire's The Scalp Serum comes into play. 

This unique product is dermatologist-tested and proven to show results. Its hydrating qualities are attributed to hyaluronic acid, while niacinamide is utilized to fortify the scalp. 

It's worth noting that a healthier scalp paves the way for thicker, more vigorous hair. 

Adding to its potency, the serum also includes a peptide blend that's been scientifically demonstrated to accelerate hair growth

As an added bonus, this product is oil-free, making it suitable for various hair and scalp types.

Shop now

9. Vegamour GRO Hair Serum

best hair serum

With over 2,000 positive reviews, Vegamour’s GRO Hair Serum is a crowd-favorite when it comes to boosting hair volume and thickness. 

Its plant-based formulation is brimming with nutrient-rich ingredients like mung bean, curcumin from turmeric, and antioxidant-packed red clover. 

These natural elements work together to reduce shedding and enhance the thickness of your hair. According to Vegamour, with daily use, you can expect fuller hair within three to four months. 

This serum not only caters to your hair needs but also speaks to the conscious consumer with its eco-friendly glass bottle, echoing the brand's commitment to sustainability.

Shop now

How to choose the best hair treatment serum?

Choosing the best hair treatment serum largely depends on your specific hair type and concerns. Identify your hair's needs - such as moisture, volume, shine, or strength - and look for a serum that targets those areas.

Also, consider your hair type: whether it's straight, wavy, curly, or oily, and if it's fine, medium, or thick, as certain serums are specifically formulated for different hair types.

Understand your hair’s needs

Firstly, you must recognize what your hair needs the most. Do you struggle with dryness, frizz, lack of volume, or hair damage? Choose a serum that tackles your primary hair concerns.

For example, if you have dry hair, a hydrating serum with ingredients like argan or coconut oil would be beneficial.

Consider your hair type 

Hair serums are not one-size-fits-all. A serum that works great for fine, straight hair might weigh down curls or not be moisturizing enough for oily hair. 

Be sure to read the product descriptions to find out if a serum is right for your specific hair type.

Check the ingredient list

Look for high-quality, nourishing ingredients that will benefit your hair. These can include natural oils, vitamins, proteins, and more. 

However, be wary of products with a high alcohol content, as these can dry out your hair.

Read reviews and recommendations 

Take the time to read product reviews from people with similar hair types and concerns. This can provide insight into how well a product works. 

Also, consider recommendations from professionals such as hairstylists or trichologists.

Conclusion

Hair serums are an effective way to address various hair issues and concerns. 

These potent potions not only target specific problems like dryness, frizz, or thinning, but they also overall enhance the health and appearance of your locks. 

The nine serums featured in this blog post, including Bio Pilixin Serum known for combating hair loss, represent some of the best on the market, each catering to diverse hair types and concerns.

Selecting the right hair serum for you largely depends on understanding your hair type and needs. 

Always consider the ingredients, read reviews, and consult with professionals if you're unsure. 

Remember, your hair deserves the same level of care and attention as any other part of your body. 

With the right hair treatment serum, you can enhance the vitality of your hair, flaunting radiant and lustrous locks that not only look good but also feel healthy and strong.

Step up your hair care game, delve into the world of serums, and let your hair shine to its fullest potential!

FAQs

How often should I use hair serum?

The frequency of use can depend on the type of serum and your individual hair needs. Some serums can be used daily, while others might be best used a few times a week. Always follow the instructions on the product packaging and adjust as needed based on how your hair responds.

Can I use a hair serum on oily hair?

Yes, certain hair serums can benefit oily hair. Look for lightweight serums or ones specifically formulated for oily hair. These can help to balance your scalp's oil production while still offering the protective and enhancing benefits of a serum.

Can hair serums help with hair loss?

Yes, some hair serums, like Bio Pilixin Serum, are formulated with ingredients aimed at nourishing hair follicles and supporting scalp health and potentially promoting hair growth.

Can I use a hair treatment serum if I have colored or chemically treated hair?

Absolutely! In fact, hair that's been colored or chemically treated often needs extra nourishment and protection, which hair serums can provide. Look for serums that are specifically safe for colored or treated hair, and that offer benefits like hydration, shine, and color protection.

Should I apply hair serum to wet or dry hair?

It depends on the specific product and your hair type. Some serums are best applied to damp hair after washing, as this allows for better absorption and distribution. Other serums might be designed for use on dry hair to tame frizz, add shine, or provide heat protection. Always check the usage instructions on the product.

References:

  1. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8808739/
  2. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7522433/
  3. https://pubmed.ncbi.nlm.nih.gov/33061509/

Read more: 

Luat Duong

Luat Duong is a Copenhagen-based writer and content strategist specializing in hair loss and health. His work has been featured in MyHealthGuide, The Right Hairstyles, and Woman's Era. He is a graduate of Vaasa University. You can connect with him on LinkedIn.